Lion’s Mane Mushroom: A Gateway to Cognitive Wellness

March 13, 2024

In the quest for optimal cognitive function and brain health, it is beneficial to explore various natural remedies and supplements. Among these, Hericium erinaceus, commonly known as Lion’s Mane mushroom, has garnered attention for its potential cognitive benefits. 

Hericium Erinaceus SAP is a hot water-extracted mushroom. Hericium erinaceus (HE) is also known by its common name, lion’s mane. The name comes from its cascading white spines reminiscent of a Lion’s Mane. It has been called “nature’s nutrient for the neurons” because of its ability to stimulate production of nerve growth factor (NGF). NGF plays an important role in both the central and peripheral nervous systems, and low levels have been associated with early stages of disorders such as dementia and Alzheimer’s disease. Hericium erinaceus has also demonstrated a beneficial effect on gastric mucosa damage seen with ulcerations. Hericium erinaceus has a positive impact on immune health and can support a healthy immune response.

Some of the cognitive benefits found in studies using Lion’s Mane include:

  • Neuroprotective potential – a study explored the neuroprotective effects of Lion’s Mane extract. The findings revealed its ability to mitigate oxidative stress and inflammation in the brain, crucial mechanisms in preserving cognitive function and staving off age-related decline.

  • Cognitive Enhancement: Research documented in the International Journal of Molecular Sciences investigated the impact of Lion’s Mane supplementation on cognitive function in mice. The results showcased improvements in memory and learning abilities, suggesting a promising role for Lion’s Mane as a natural cognitive enhancer.

  • Stimulation of Nerve Growth Factor (NGF): Lion’s Mane has been shown to promote the production of NGF in the brain. It is instrumental in nerve cell growth, maintenance, and survival, indicating Lion’s Mane’s potential for neuroregeneration and repair processes.

  • Improvements for Mild Cognitive Impairment (MCI): A clinical trial, as reported in Phytotherapy Research, investigated Lion’s Mane supplementation in individuals with MCI. Encouragingly, participants exhibited improvements in cognitive function and daily living activities compared to those receiving a placebo, suggesting therapeutic potential for addressing cognitive decline associated with aging.

  • Managing Neurological Disorders: Emerging research, such as a study published in Frontiers in Pharmacology, suggests Lion’s Mane’s promise in managing neurological disorders like Alzheimer’s and Parkinson’s diseases. The mushroom’s ability to inhibit beta-amyloid plaque formation and reduce neuroinflammation offers avenues for exploring its therapeutic applications in these conditions.

Lion’s Mane mushroom has emerged as an important supplement in the quest for cognitive well-being. Its neuroprotective, cognitive-enhancing, and potential therapeutic properties promote brain health and resilience. Lion’s Mane offers a holistic approach to nurturing cognitive vitality. However, it’s imperative to consult healthcare professionals before integrating any new supplement regimen, particularly for individuals with underlying health conditions or those under medication. Longév Clinic has Lion’s Mane in our dispensary, please ask about it during your next naturopathic appointment.


Neurohealth Properties of Hericium erinaceus Mycelia Enriched with Erinacines – PMC

The Acute and Chronic Effects of Lion’s Mane Mushroom Supplementation on Cognitive Function, Stress and Mood in Young Adults: A Double-Blind, Parallel Groups, Pilot Study

Prevention of Early Alzheimer’s Disease by Erinacine A-Enriched Hericium erinaceus Mycelia Pilot Double-Blind Placebo-Controlled Study


explore more